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While DAPOXITIME LONG is generally well-tolerated, some individuals may experience mild to moderate side effects, especially when first starting treatment. These effects usually subside as the body adjusts to the medication.

However, if you experience prolonged or severe side effects, such as chest pain, vision changes, or a prolonged erection lasting more than 4 hours (priapism), seek immediate medical attention.

• The medication is metabolized primarily in the liver by the CYP3A4 enzyme.
• Drugs that inhibit CYP3A4 will increase Sildenafil concentration (e.g., ketoconazole).
• Drugs that induce CYP3A4 will decrease Sildenafil concentration (e.g., rifampin).
• This is why discussing all medications, including herbs, is critical.
• St. John's Wort, an herbal supplement, can reduce Sildenafil levels.
• Erythromycin and clarithromycin (antibiotics) can increase levels.
• The terminal half-life of Sildenafil is about 3-5 hours in healthy young men.
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• Approximately 80% of the dose is excreted in feces, 13% in urine.
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