Comparing Popular UK Erectile Dysfunction Drugs

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The Sildenafil in Viagra is one of a number of PDE5 enzyme inhibitors. Alternatives include Tadalafil (Cialis), Vardenafil (Levitra) and Avanafil (Spedra) – for which you do still need a prescription. Join more than 100,000 happy customers who have used Manual No names, no logos, no delivery fee. All content on this page has been medically reviewed by: Hassan Thwaini, Clinical Pharmacist and Copywriter, Master of Pharmacy (MPharm) on 30 March, 2026. Find the clinically proven ED treatment that suits you best. 4.6* from over 33,000 people like you. Here’s the breakdown of what happens in your body to get the blood flowing again:1 Arousal triggers cGMP, a molecule that boosts blood flow to the penis and helps you get an erection.

Discreet Packaging

Our pharmacist will prescribe you the correct dose of Sildenafil to best treat your ED. The normal dosage of Sildenafil is 50mg, and this has the desired effect for the vast majority of men who use it. It can also be taken in 25mg and 100mg forms. When you take Sildenafil for the first time, the most important thing is to relax and enjoy some sexual stimulation. This will give the drug the best chance to kick in and help you get the firm erection you’re looking for.

UK-based clinical team

Learn more about first-time use of Sildenafil on our blog. Sildenafil is the world’s most counterfeited drug – and there are many online vendors trying to pull a fast one. So if it looks like too much of a good deal, it most likely is. Sildenafil was first brought to the UK market by cenforce 200 tablets global pharmaceutical giants, Pfizer, and it was only available under their brand name, Viagra. This exclusivity meant the price tag was high and many men couldn’t afford this type of legitimate ED medication. In people with ED, an enzyme called PDE5 breaks down cGMP too quickly, reducing blood flow and causing the erection to fade. ED treatments block PDE5, helping more blood reach the penis. This leads to firmer, longer-lasting erections. Treat the symptoms with ED medication, and get 50% off an ED blood test to investigate the underlying cause.2-5 1 in 3 men with ED have low-T If left untreated, leads to higher risk of stroke and heart attacks 62% of people with heart disease have ED If left untreated, vascular problems can be fatal 65% of men with diabetes have ED Around 80-85% of people with type 2 diabetes are overweight or obese Untreated diabetes can lead to blindness, kidney failure and heart attacks Reclaim your confidence in the bedroom with clinically proven ED treatments delivered to your door. Take a simple blood test to uncover what’s really going on. Speak with our men’s health experts to make a plan that tackles the root cause, not just the symptoms. Around 40% of men with erectile dysfunction have an underlying health issue that may contribute to their symptoms.1 We provide a comprehensive assessment of key health areas linked to ED to help identify possible causes. Optimal levels of testosterone ensure healthy bodily functions. Lower levels of the hormone can impact libido, sexual function, energy, and mood. Erectile dysfunction can be an early warning sign of coronary heart disease. This test will help sex tablet for men price you to determine your risk and take action sooner. High cholesterol levels impact blood flow around the body and can therefore be a contributor to erectile dysfunction. This test will give you a clear picture of your levels.

It's not just about being ready in the bedroom. Specialists in medicine, nutrition, performance, and sexual health. BSc (Hons) MBBS MRCGP AFHEA MA (Hons) AFMCP I felt fairly comfortable talking to my partner about my ED.

Medication Common Side Effects Serious Side Effects Precautions
Viagra Headache, flushing, nasal congestion Priapism, vision changes Avoid with nitrates
Cialis Muscle aches, indigestion Hypotension Alcohol caution
Levitra Dizziness, facial flushing Sudden vision loss Medical consultation for heart issues
Spedra Flushing, dizziness Rare allergic reactions Not for use with certain medicines

I was actually more nervous speaking to the doctor about it, but when I found Numan, I realised it was very easy to get it sorted discreetly. I think any sort of relationship where you can’t fulfil someone’s needs is a bit of a deal breaker. It’s given me confidence as I know it’s going to work.

Product Dosage Quantity + Bonus Price
Cialis Generic10mg60 + 6 Pills105.81€ 100.77€
Kamagra Oral Jelly100 mg110 + 9 Sachets334.87€ 318.92€
Cialis Generic20mg360 + 10 Pills427.34€ 406.99€
Levitra Soft Tabs20mg90 + 6 Pills241.31€ 229.82€
Kamagra Oral Jelly100 mg90 + 8 Sachets303.56€ 289.10€
Kamagra Gold50 mg12 Pills47.30€ 45.05€
Levitra Original20mg76 + 4 Pills344.39€ 327.99€
Tadalista Super Active20mg180 + 20 Pills521.59€ 496.75€
Viagra Generic200mg120 + 8 Pills204.80€ 195.05€
Viagra Original100mg4 Pills40.94€ 38.99€
Cialis Black80mg10 Pills43.27€ 41.21€
Levitra Generic10mg180 + 10 Pills246.74€ 234.99€
Viagra Generic150mg120 + 8 Pills177.58€ 169.12€
Kamagra Soft Tabs100mg120 + 6 Pills311.78€ 296.93€
Kamagra Soft Tabs100 mg84 + 4 Pills233.05€ 221.95€
Viagra Professional100mg180 + 4 Pills337.30€ 321.24€

Numan is brilliant as there are so many different options to choose from. I tried a few different plans and found that a daily treatment suited me best. Whenever love is in the air, I’m ready.

ED Treatment Online, Discreetly Delivered

Women should never take Sildenafil, and nobody under the age of 18 – male or female. And, of course, if you don’t have erectile dysfunction, you shouldn’t use Sildenafil. If you’ve been told by the doctor not to have sex – perhaps due to lack of fitness or a recent acute myocardial infarction (AMI) or stroke, you should also avoid Sildenafil. And generally, men who have had other heart problems needing care. These include: low blood pressure or uncontrolled high blood pressure (pulmonary arterial hypertension); unstable angina (chest pain), irregular heartbeat or palpitations (arrhythmia); valvular heart disease; cardiomyopathy; problems causing blood flow issues.

What are common causes of erectile dysfunction?

Other conditions may prohibit the use of Sildenafil, such as anatomical deformation of the penis (e.g. And you should also confirm with your GP if you’re taking nitrates (nicorandil or other nitric oxide donors e.g. amyl nitrite), or recreational stimulant drugs (e.g. cocaine, MDMA); riociguat or other guanylate cyclase stimulators; ritonavir; CYP3A4 inhibitors, e.g. Before using Sildenafil, please read the Patient Information Leaflet supplied with your medication. It’s given me a lot more confidence in myself and with my partner. I had a few misconceptions about the treatment which Numan has explained really well. It's just given me a lot more self-belief when it comes to being intimate. Rabijewski M, Papierska L, Kozakowski J, Zgliczyński W.

Aspect Details Authority Notes
Prescription Requirement Mandatory for Sildenafil, Vardenafil, Tadalafil Medicines and Healthcare products Regulatory Agency (MHRA) Ensures safety and efficacy
Online Purchase Legality Must be from licensed UK pharmacies or authorized providers MHRA, General Pharmaceutical Council (GPhC) Risk of counterfeit products
Age Restrictions Typically 18 years and above UK Law Age verification essential
Import Restrictions Strict regulations on importing prescription meds HM Revenue & Customs (HMRC) Risk of confiscation for unapproved products

The high prevalence of testosterone deficiency in buy online lovegra population of Polish men over 65 years with erectile dysfunctions. Olinic DM, Stanek A. Vascular diseases: Etiologic, diagnostic, prognostic, and therapeutic research. Erectile dysfunction and diabetes: A melting pot of circumstances and treatments.

Vardenafil 20mg - 4 Tablets

In 2013, however, Pfizer’s patent expired, and it became legal to manufacture the drug under its generic name, Sildenafil. Here at Manual, we provide a digital consulting service. The recommended retail price for branded Viagra Connect is equivalent to about £5 per pill. At Manual, the same Sildenafil is available for as little as £2 per tablet. Firstly, it’s important to know that side effects are rare.

Further reading

However, when they do occur, the most common side effects of Sildenafil are: headaches, facial flushing, indigestion, nasal congestion, dizziness, nausea, hot flushes, vision changes (such as having a blue colour tinge, or blurred vision). Serious side effects can become more common when Sildenafil is misused, mixed with excessive alcohol, or due to drug interactions with other medications. Although rare, Priapism (an erection that lasts for 4 hours or more) is a serious side effect that requires immediate medical attention. Please read the patient information leaflet carefully for a full list of side effects and advice. As with any drug, if you notice any adverse effects, stop taking it and seek medical advice. McMurray JG, Feldman RA, Auerbach SM, Deriesthal H, Wilson N, Multicenter Study Group. Long-term safety and effectiveness of sildenafil citrate in men with erectile dysfunction. Long-term safety and tolerability of tadalafil in the treatment of erectile dysfunction. 2004;45(3): 339–344; discussion 344-5. Answer a few simple questions to get the treatment you need. Erectile dysfunction affects approximately half of all men between 40 and 70 years old in the UK. If you’re searching for the best erectile dysfunction treatment UK options, you’re certainly not alone, and the good news is that effective treatments are widely available. Finding the right solution can feel overwhelming. With various medications, therapies, and approaches on offer, knowing where to start isn’t always straightforward. As a consultant urological surgeon, Mr Ashwin Sridhar regularly helps men navigate these options, providing expert guidance on treatments that suit their individual circumstances and underlying health conditions. This guide compares six proven erectile dysfunction treatments available in the UK. You’ll learn how each option works, their key differences, and what to consider when choosing between them, whether you’re exploring NHS pathways or private specialist care. A private urology consultation provides the most thorough assessment of erectile dysfunction and often reveals underlying health conditions that simpler solutions might miss. When you book with a specialist urologist, you gain access to comprehensive diagnostic tests, personalised treatment plans, and ongoing support that addresses the root causes of your symptoms rather than just managing them temporarily.

Your urologist will start by taking a detailed medical history, including questions about when your symptoms began, how they affect your relationships, and any other health conditions you have. They’ll perform a physical examination to assess your cardiovascular health, check for signs of hormonal imbalances, and evaluate nerve function in the genital area.

This initial assessment helps identify whether your erectile dysfunction stems from physical causes, psychological factors, or a combination of both.

Cialis (Tadalafil) 2.5mg - 28 Tablets

Curated by Dr. Earim Chaudry, Manual Medical Director When and how should I start treatment? What are the common side effects of Sildenafil? At Manual, we are experts on erectile dysfunction. In many patients, it can be caused by a combination of factors, and so do we advise having a GP checkup.

What does Tadalafil look like?

If you decide to treat your ED, an oral medication like Sildenafil is the most popular way to start. Some men find just knowing it’s available to help improves their sexual confidence, and 80% of men who take Sildenafil will achieve erections strong enough for sex. When and how should I start treatment? Here at Manual, all of our medication comes from the officially accredited Manual Pharmacy. Before you buy, you will receive a consultation from one of our clinicians, who are all registered with the UK’s General Pharmaceutical Council. Specialists investigate several key risk factors during your consultation.