3 DOSAGE FORMS AND STRENGTHS

A 10-mg dose of vardenafil is approximately equivalent to 50 mg of sildenafil, or Viagra. This is because the chemical composition of vardenafil is different from that of sildenafil. Vardenafil is taken 25 to 60 minutes before sex.

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As the blood accumulates in the penis, an erection results. Vardenafil belongs to a class of drugs called phosphodiesterase type-5 (PDE5) inhibitors. A PDE5 inhibitor stops PDE5 from cenforce d 160 constricting the arteries. By relaxing the arteries, vardenafil enhances blood flow when a man is sexually aroused. The active ingredient works on the chain of reactions within the penis during arousal.

Available Strengths (2)·Most prescribed

When a male is sexually aroused, nitric oxide is released into his penis, and this triggers a chain of reactions. This causes an enzyme, guanylate cyclase, to produce cyclic guanosine monophosphate (cGMP). cGMP regulates the contraction and dilation, or expansion, of blood vessels that carry blood to and from the penis. The chemical reaction causes the vessels that supply the penis to dilate, while those removing blood from the penis contract. Phosphodiesterase-5 (PDE5), another enzyme breaks down or destroys cGMP. The effect lasts for up to 5 hours. A maximum of one tablet can be used every 24 hours. Orodispersible tablets must be left to dissolve on the tongue before swallowing. They should not be taken with any kind of drink. The drug will not work unless the man is sexually aroused, so foreplay will normally be necessary. Vardenafil can be taken with or without food, but drinking alcohol is not advised, as it reduces the chance of getting an erection. Alcohol can also increase the risk of adverse effects. As with all medications, adverse effects and interactions can occur when using vardenafil. One in 10 men will experience headache. In most cases, these disappear within a few hours. ringing in the ears, or sudden hearing loss swelling in the ankles, hands, libido for women or feet The patient should stop using vardenafil if these occur.

This can lead to hives, difficulty breathing, and swelling of the face, tongue, and throat. If these symptoms appear, it should be treated as a medical emergency. Very rare side effects may include priapism, when an erection lasts longer than 4 hours. If an erection lasts too long, the individual should seek medical attention. Visual disturbances can happen when blood pressure drops in the eye. The individual may see a blue tinge to objects, and they may have difficulty distinguishing between the colors green and blue. Very rarely, there may be a sudden deterioration in vision in one or both eyes. This can indicate a heart condition, an existing eye problem, high cholesterol, diabetes, or hypertension. If any sudden loss of vision occurs, the individual should stop taking the medication and seek medical help immediately. Vision problems are most likely in patients with other conditions, such as heart or coronary artery disease, diabetes, and high cholesterol. Vision problems are more likely to happen if the person smokes, or if they are aged over 50 years. Using vardenafil with some other drugs can lead to serious adverse effects. a potentially dangerous drop in blood pressure, or hypotension There is also a risk of stroke and heart attack. A man should not use vardenafil if he is taking nitrate drugs, such as riociguat (Adempas), or other nitrate drugs for chest pain or heart problems. It should not be used with the recreational drugs, amyl nitrate and butyl nitrate, also known as poppers.

5.1 Cardiovascular Effects

This drug is used on an as needed basis. Do not use more often than told by the doctor. Store at room temperature protected from light. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.

What are some side effects that I need to call my doctor about right away?

Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area. If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else’s drugs. Other drugs that may interact include, but are not limited to: drugs for prostate problems, blood pressure, or heart rhythm disorders Grapefruit juice contains a chemical that makes adverse effects more likely, so it should not be consumed while using vardenafil.

Before Using

When cGMP is destroyed, the blood vessels return to their normal size, effectively ending the erection. In this way, it allows cGMP to work for longer. As a result, it helps prolong an erection. Vardenafil is available in tablets of 2.5 milligrams (mg), 5 mg, 10 mg, and 20 mg. The first dose is normally 10 mg. Optum Perks is owned by RVO Health. By clicking on this link, we may receive a commission. Patients should tell their doctor about all their medical conditions and any other medications or supplements they use before taking vardenafil.

• Vardenafil is a selective inhibitor of PDE5 enzyme.
• It is classified as a prescription medication.
• Online purchases should be approached with caution.
• Always disclose your health history to your doctor.

This is especially important if they have: a deformity in the shape of the penis, such as Peyronie’s disease a heart condition, such as arrhythmia, heart failure, or angina a family history of a rare heart condition known as long QT syndrome hemophilia or some kind of bleeding problem hypotension (low blood pressure) or hypertension (high blood pressure) multiple myeloma, leukemia, sickle cell anemia, or some other kind of blood cell problem non-arteritic anterior ischemic optic neuropathy (NAION) damage to the retina of the eye retinitis pigmentosis, a rare genetic eye disease They should also tell the doctor if they have ever experienced priapism, a seizure, or if they have recently had a stroke or a heart attack.

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UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at Vardenafil, also known by the brand name Levitra, is a prescription medication that treats male erectile dysfunction. Erectile dysfunction is when a man is unable to get or sustain an erection. It usually happens because the arteries that carry the blood to the penis are too narrow.

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Vardenafil increases blood flow to the penis. Its action is similar to that of sildenafil, or Viagra, but Viagra lasts between 2 and 4 hours, while Levitra lasts 4 hours. During a penile erection, the penis fills with blood. The blood vessels that supply the penis with blood expand, or dilate, and the vessels that take blood away from the penis contract. The two large chambers in the penis, known as the corpus cavernosa, fill with blood. Levitra is available to purchase online, but users should consider the above points and check with their health provider first.

• Vardenafil is effective for up to 4-5 hours.
• Do not use if allergic to vardenafil or similar drugs.
• Overdose symptoms may include prolonged erections.
• Medical advice is essential for any severe side effects.

If any adverse effects occur, users are encouraged to Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health.

4.2 Guanylate Cyclase (GC) Stimulators

However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. You may report side effects to your national health agency. You may report side effects to the FDA at 1-800-332-1088.

What are the most common side effects of vardenafil?

You may also report side effects at Use this drug as ordered by your doctor. Place on your tongue and let it dissolve. Do not take this drug out of the blister pack until you are ready to take it. Take this drug right away after opening the blister pack. Do not store the removed drug for future use. Our providers may not see and/or treat all topics found herein. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Ignite Healthwise, LLC. Vardenafil is a medication that treats erectile dysfunction. ED is the inability to achieve and sustain an erection suitable for sexual intercourse. This medication works by increasing blood flow to your penis, which helps you maintain an erection. Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. VARDENAFIL (var DEN a fil) treats erectile dysfunction (ED).

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Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. This generalized information is a limited summary of diagnosis, treatment, and/or medication information.

Other Medical Problems

It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider’s examination and assessment of a patient’s specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. It works by increasing blood flow to the penis, which helps to maintain an erection. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

They need to know if you have any of these conditions: Eye or vision problems, including a rare inherited eye disease called retinitis pigmentosa Heart disease, angina, a history of heart attack, irregular heart beats, or other heart problems History of blood diseases, such as sickle cell anemia or leukemia An unusual or allergic reaction to vardenafil, other medications, foods, dyes, or preservatives Take this medication by mouth with water.